Targeted (re)-sequencing - In-depth analysis of selected regions of interest

For studies of any size, from small projects to up to thousands of samples

Target re-sequencing of enriched or amplified genomic regions of interest enables their in-depth analyses and hence facilitates the discovery of rare and common SNPs, insertions, and deletions in a statistically relevant numbers of samples.

Systematically identify disease-causing genes and mutations in coding and non-coding exonic regions through using predefined catalog enrichment kits for human or the classic model vertebrate mouse. Custom enrichment designs make it possible to focus your genetic predisposition, disease and association studies on individual, specific candidate loci.

Locus-specific amplification of small target regions followed by ultra-deep sequencing is perfectly suited to detect rare and common mutations in complex samples, perform viral subtyping and to phylogenetically characterize microbial ecosystems.

Enrichment

= In solution enrichment of specific genomic regions
+ Illumina HiSeq 2000 | single or paired end reads
+ made-to-measure bioinformatics for every budget: From raw data via the mapping right through to SNP and InDel analysis including correlation to relevant biological information as e.g. amino acids exchanges

Amplicon sequencing

= Roche GS FLX+ | single reads
+ made-to-measure bioinformatics for every budget: From raw data via the mapping right through to the SNP analysis