Hybrid strategies as the means to success
A genome project sequenced with three technologies
Exploit our many years of experience in genome projects - de novo and re-sequencing projects of any size – to obtain the most efficient result, e.g.:
De novo sequencing
= Backbone sequencing with Roche GS FLX
+ assembly validation, correction of the homo-polymers & contig orientation using paired-end sequencing of different sized insert libraries on Illumina Genome Analyzer IIx
+ finishing using Sanger sequencing on ABI 3730 xl
+ made-to-measure bioinformatics for every budget: From raw data via the assembly right through to the annotation
Re-sequencing
= Illumina Genome Analyzer IIx | single or mate pair reads for the analysis of SNPs, InDels or re-arrangements
+ made-to-measure bioinformatics for every budget: From raw data via the mapping right through to the SNP and InDel analysis
Targeted re-sequencing | enrichment
= Enrichment of specific regions of the genome
+ Illumina Genome Analyzer IIx | single reads
+ made-to-measure bioinformatics for every budget: From raw data via the mapping right through to the SNP analysis
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